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Brand Product Name SKU Replacement SKU Updates to Formula/Label/Packaging Market Date Date Added
Pure Encapsulations Probiotic-5 PRB6C-C No change Add probiotic stabilizing ingredients as non-medicinal ingredients per Health Canada probiotic monograph. Revise warning.

Changes to Non-Medicinal Ingredients:
  • Add “Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, sucrose, acacia gum, trehalose, dextrose, sodium chloride).”
Revised Warning:
  • Do not use this product if you have an immune-compromised condition or are taking tetracycline. Consult a healthcare practitioner prior to use if you have fever, vomiting, bloody diarrhoea or severe abdominal pain. Stop use and consult a healthcare practitioner if symptoms of digestive upset occur, worsen or persist beyond 3 days.
Address updated to Richmond Hill, ON L4S 0J7

New label V10 		10/22/2021 11/01/2021
Pure Encapsulations Probiotic G.I. PGI6C-C No change Add probiotic stabilizing ingredients as non-medicinal ingredients per Health Canada probiotic monograph. Revise warning, recommended use, recommended dose & shelf life. Changes to Non-Medicinal Ingredients:
  • Add “Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, trehalose, sucrose, dextrose, sodium chloride, acacia gum).”
Revised Warning:
  • Do not use this product if you have an immune-compromised condition or are taking tetracycline. Consult a healthcare practitioner prior to use if you have fever, vomiting, bloody diarrhoea or severe abdominal pain. Stop use and consult a healthcare practitioner if symptoms of digestive upset occur, worsen or persist beyond 3 days.
Revised Recommended Use:
  • Add “Helps support gastrointestinal health.”
Revised Recommended Dose:
  • Adults, Adolescents and Children (6 years and older): Take 1 capsule 1-2 times daily or as directed by a healthcare practitioner. Take at least 2-3 hours before or after taking antibiotics.
Change shelf life From 24 months To 18 months

Address updated to Richmond Hill, ON L4S 0J7

New label V5 		10/29/2021 11/01/2021
Pure Encapsulations Probiotic 123 PRO6C-C No change Add probiotic stabilizing ingredients as non-medicinal ingredients per Health Canada probiotic monograph. Revise warning.

Changes to Non-Medicinal Ingredients:
  • Add “Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, acacia gum, trehalose, sucrose).”
Revised Warning:
  • Do not use this product if you have an immune-compromised condition or are taking tetracycline. Consult a healthcare practitioner prior to use if you have fever, vomiting, bloody diarrhoea or severe abdominal pain. Stop use and consult a healthcare practitioner if symptoms of digestive upset occur, worsen or persist beyond 3 days.
Address updated to Richmond Hill, ON L4S 0J7

New label V3 		06/16/2021 11/01/2021
Pure Encapsulations OsteoBalance OB2C-C No change Update NPN, Trademark. Revise Medicinal Ingredient label claims to align with new product license per capsule (no formulation change), revise Recommended Dose to align with USA label.
  • New NPN 80106995
  • Update trademark to “AlbionTM and DimaCalTM are trademarks of Albion Laboratories, Inc.”
Changes to medicinal ingredients:
  • Change Boron label claim from 0.3 mg to 283 mcg
  • Change Calcium label claim from 172 mg to 171.3 mg
  • Change Copper label claim from 360 mcg to 333.3 mcg
  • Change Magnesium label claim from 21.4 mg to 21.3 mg
  • Change Manganese label claim from 0.71 mg to 0.7 mg
  • Change Zinc label claim from 4.3 mg to 4 mg
Update Recommended Dose:
  • Adults: Take 3 capsules 1-2 times daily with meals, a few hours before or after taking other medications or natural health products, or as directed by a healthcare practitioner. Consult a healthcare practitioner for use beyond 3 months.
Address updated to Richmond Hill, ON L4S OJ7

New label V8 		07/06/2021 08/04/2021
Pure Encapsulations Probiotic 50B PR506C-C Reformulation: Revise probiotic strains, add probiotic stabilizing ingredients as Non-Medicinal Ingredients. Update NPN, UPC, Product code & Warnings.

Changes to probiotic strains:
  • Change Lactobacillus plantarum (Lp-115) FROM 15 billion CFU TO 5 billion CFU
  • Change Bifidobacterium animalis subsp. lactis (Bl-04) FROM 10 billion CFU TO 5 billion CFU
  • Change Bifidobacterium longum subsp. longum (Bl-05) FROM 5 billion CFU TO 15 billion CFU
  • Remove Lactobacillus rhamnosus (Lr-32)…10 billion CFU
  • Add Lactobacillus rhamnosus GG (5 billion CFU), Bifidobacterium bifidum Bb-06 (5 billion CFU) & Lactobacillus gasseri Lg-36 (5 billion CFU)
  • Change to Non-Medicinal Ingredients:
  • Add “Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, trehalose, sucrose, sodium chloride, sodium ascorbate, acacia gum).”
    • Add to Warning: “Do not use this product if you are taking tetracycline, kanamycin, or clindamycin.”
  • New Item # PR56C-C
  • New NPN 80106559
  • New UPC 7 66298 02356 4


New label V1 		05/14/2021 05/13/2021
Pure Encapsulations Metabolic Xtra MX9C-C
MX29C-C
 Reformulation: Update Medicinal ingredient Chromium, NPN, UPC, and product code.
  • New Item# MX29C-C
  • New NPN 80107768
  • New UPC 7 66298 02362 5
  • Change label claim of Chromium FROM chromium dinicocysteinate…135 mcg TO chromium polynicotinate…200 mcg
  • Replace trademark Zychrome® with ChromeMate®
    • New label V1
04/29/2021 05/13/2021
Pure Encapsulations Amino-NR ANR31C-C
ANR41C-C
 Reformulation – addition of vitamin B12, removal of alpha-Ketoglutaric acid
  • Add Vitamin B12 (from adenosylcobalamin) 333.3 mcg
  • Remove Alpha keto-glutarate
  • New Item # ANR41C-C
  • New UPC 7 66298 02349 6
  • New NPN 80105744
  • Revised recommended daily dose (change from 1-2 capsules 3 times daily to 3 capsules daily) per updated Product Licence.
  • Address updated on label: Richmond Hill, ON L4S 0J7
New label V1 		3/18/2021 04/07/2021
Pure Encapsulations Vitamin E DE9C-C No change Label Revision: revise label claim for Vitamin E
  • Vitamin E label claim from 268 mg AT to 260 mg AT
  • Change NPN from 80075368 to 80105878
  • Certified Gluten-Free logo added to label
Label update from V1 to V2 		2/1/2021 03/03/2021
Pure Encapsulations PureGenomics Multivitamin PGM26C-C No change Reformulation: Revise excipients / Non-Medicinal Ingredients to replace ascorbyl palmitate, update source of Vitamin C. Update RHDC address.
  • Add magnesium citrate
  • Remove ascorbyl palmitate
  • Change source of Vitamin C from ascorbic acid to ascorbic acid/ascorbyl palmitate
  • Change RHDC address from Richmond Hill, ON L4C 0L8 to Richmond Hill, ON L4S 0B4
 11/1/2020 11/25/2020
Pure Encapsulations LiquiNutrients LQN22C-C Reformulation: Revise Active / Medicinal Ingredients to remove molybdenum, update source of Chromium.

Update product code, update NPN.
  • Remove Molybdenum
  • Change source of Chromium from chromium polynicotinate to chromium nicotinate glycinate
  • Change product code from LQN22C to LQN32C
  • Change NPN from 80081924 to 80095756
New Label V2 		10/1/2020 11/25/2020
Pure Encapsulations Amino Replete AMR5C-C Reformulation: revise active ingredients and non-medicinal ingredients, revise scoop size, serving size and bottle size.
  • revise arginine from 250 mg to 200 mg per scoop
  • revise L-tryptophan from 48 mg to 60 mg per scoop
  • revise L-threonine from 161 mg to 160 mg
Non-medicinal ingredients updated: natural vanilla, strawberry, and lemonade flavors with other natural flavors, citric acid, malic acid, purified stevia leaf extracts

Scoop size revised from 10cc (9 g) to 5cc (4 g)

Net weight per container changed from 540 g to 240 g

New Item# AMR2C-C

New NPN: 80096397

New UPC: 7 66298 02225 3

New label V1 		8/1/2020 11/25/2020
Pure Encapsulations Glucose Support Formula GSF6C-C No change Ingredient Change: Revise extract ratio of Gymnema Leaf Extract from 20-25:1 to 25-30:1

Update trademark for ChromeMate® brand niacin-bound chromium. ChromeMate® & logo are trademarks of Lonza or its affiliates.

Label updated from V7 to V8 		7/1/2020 11/25/2020
Pure Encapsulations Vascular Relax VR21C-C No change Raw material specification change: revise hawthorn flower and leaf extract ratio from 5-7:1 to 3-6:1

Label updated from V5 to V6 		5/1/2020 11/25/2020
Pure Encapsulations UltraNutrient UVC1C-C No change Raw material specification change: revise hawthorn flower and leaf extract ratio from 5-7:1 to 3-6:1

Update trademark for ChromeMate®. ChromeMate® & logo are trademarks of Lonza or its affiliates.

Label updated from V5 to V6 		5/1/2020 11/25/2020
Pure Encapsulations Iron Liquid IRLC-C No change Excipient change: revise lecithin source in SunActive® Fe
  • change from rapeseed lecithin to sunflower lecithin
Label updated from V3 to V4 		5/1/2020 11/25/2020
Pure Encapsulations Puremelt B12 Folate PMLB9C-C No change Reformulation: updated excipients & flavouring to allow for sale/marketing in EU
  • revised flavourings from natural cherry flavour to cherry/mixed berry flavour
  • added hyprolose (tablet binder) & malic acid (acidifier)
Label updated from V1 to V2 		11/1/2019 11/25/2020
Pure Encapsulations Probiotic-5 PRB6C-C No change Reformulation: excipient change, replace rice starch with hypoallergenic plant cellulose

Label update from V8 to V9 		7/1/2019 11/25/2020
Pure Encapsulations Probiotic 50B PR506C-C Reformulation: excipient change, replace rice starch with hypoallergenic plant cellulose

Label update from V4 to V5 		6/1/2019 11/25/2020
Pure Encapsulations Saccharomyces boulardii SB6C-C No change Reformulation: excipient change, replace rice starch with hypoallergenic plant cellulose

Label update from V4 to V5 		6/1/2019 11/25/2020
Pure Encapsulations Probiotic 123 PRO8C-C
PRO6C-C
 Reformulation: excipient change, replace rice starch with hypoallergenic plant cellulose

Revise dose for children age 1-3 years from 1 scoop to 1/2 scoop daily

Label update from V1 to V2 		6/1/2019 11/25/2020
Pure Encapsulations FocusPlus (Formerly DopaPlus) DOP1C-C No change Brand Name Change (per request from Health Canada): revise brand name from DopaPlus to FocusPlus

Label change from V5 to V6 		5/1/2019 11/25/2020
Pure Encapsulations Probiotic G.I PGI6C-C No change Reformulation: excipient change, replace rice starch with hypoallergenic plant cellulose

Label update from V3 to V4 		5/1/2019 11/25/2020
Pure Encapsulations Vitamin D3 Liquid VDLC-C No change Packaging Change: Bottle will be changed from a child-proof dropper dispensing package, to a glass bottle with dispensing insert and child proof cap (no dropper) inside box

Label update from V2 to V3 		4/1/2019 11/25/2020
Pure Encapsulations Krill-plex KP6C-C No change Specification & label change: Krill oil raw material specification revision, label claims for potency markers revised
  • Astaxanthin revised from 375 mcg to 198 mcg
  • EPA revised from 75 mg to 74 mg
  • DHA revised from 45 mg to 33 mg
  • Omega-3 revised from 30 mg to 31 mg
  • Phospholipids revised from 200 mg to 248 mg
Label updated from V7 to V8 		3/1/2019 11/25/2020
Pure Encapsulations ADL II ADL6C-C
ADL9C-C
 Reformulation & brand name change: New formula will contain 300 mg of LOWAT® (a researched proprietary blend of Piper betle leaf and Dolichos biflorus seed extracts) with research showing significant support for adiponectin and weight management, and 16.7 mg Oligonol® per capsule.
  • add silica (excipient)
Brand Name change from Adipolean to ADL II

New item# ADL9C-C

New NPN: 80087665

New label V1 		3/1/2019 11/25/2020
Pure Encapsulations Glucose Support Formula GSF6C-C No change Label change: revise Gymnema Leaf Extract ratio from 25:1 to 20 - 25:1

Update label from V6 to V7 		1/1/2019 11/25/2020
Pure Encapsulations Mitochondria-ATP MATP1C-C
MATP21C-C
 Trademark change: revise creatine from Kre-Alkalyn™ to CreaPure™

New Item# MATP21C-C

New label V1 		10/1/2018 11/25/2020
Pure Encapsulations PureLean Chocolate PLC7C-C No change Reformulation: revise rice protein, add hydrolyzed guar gum & tapioca maltodextrin, improve flavour profile

New NPN: 80079046

Update label from V1 to V2 		9/1/2018 11/25/2020
Pure Encapsulations Metabolic Xtra MX9C-C No change Reformulation: revise excipients - add cellulose, revise label claim from berberine hydrochloride 350 mg to berberine (from berberine hydrochloride) 315 mg

Update label from V4 to V5 		9/1/2018 11/25/2020
Pure Encapsulations Liver GI Detox LGD6C-C No change Label change: revise artichoke extract ration from 10:1 to 19:1, revise recommended dose from 3 capsules 2 times daily to 3 capsules daily.

Updated label from V7 to V8 		8/1/2018 11/25/2020
Pure Encapsulations Liposomal Glutathione LSG6C-C No change Reformulation: revise softgel excipient - replace titanium dioxide with calcium carbonate (colorant / opacifier)

Update label from V3 to V4 		8/1/2018 11/25/2020
Pure Encapsulations Heartburn Essentials HB1C-C No change Label change: revise artichoke extract ration from 10:1 to 19:1

Updated label from V6 to V7 		8/1/2018 11/25/2020
Pure Encapsulations Buffered Ascorbic Acid ABP2C-C
ABP32C-C
 Reformulation: Nutrient amounts changing due to raw material change from: vitamin C 1,012 mg, calcium 193 mg, magnesium 108 mg and potassium 33 mg to: Vitamin C 1,220 mg; Calcium 100 mg; Magnesium 60 mg; Potassium 20 mg

New Item# ABP32C-C

New NPN: 80086187

New UPC: 7 66298 02064 4

New Label V1 		8/1/2018 11/25/2020
Pure Encapsulations PureLean Vanilla PLVS5C-C No change Reformulation: revise rice protein, add hydrolyzed guar gum & tapioca maltodextrin, improve flavour profile

New NPN: 80079046

Updated label from V3 to V4 		7/1/2018 11/25/2020
Pure Encapsulations B6 Complex B6C6C-C
B6C26C-C
 Reformulation: addition of choline, inositol and revised sources of vitamin B12
  • Vitamin B12 increased from 400 μg to 1000 μg, sources revised from methylcobalamin to methylcobalamin, adenosylcobalamin & hydroxocobalamin
  • add 30 mg choline (from choline bitartrate)
  • add 25 mg inositol
  • reduced vitamin B6 from 260 mg to 200 mg
New Item#: B6C26C-C

New NPN: 80076687

New UPC: 7 66298 11795 9

New Label V1 		7/1/2018 11/25/2020
Pure Encapsulations SP Ultimate SPU9C-C
SPU29C-C
 Reformulation: remove vitamin E & decrease amount of selenium
  • vitamin E removed
  • selenium label claim reduced from 66.6 μg to 23.3 μg
New Item# SPU29C-C

New NPN: 80081749

New UPC: 7 66298 01920 8

New label V1 		6/1/2018 11/25/2020
Pure Encapsulations LiquiNutrients LQN2C-C Reformulation: major reformulation, source changes for minerals, flavour revision, addition of fruit blend, revision of non-medicinal ingredients
  • new flavour profile: natural lemon creme flavour
  • remove folic acid, vitamin B12, inositol hexanicotinate
  • reduce zinc from 15 mg to 12 mg
  • revise vitamin D3 source (animal-source) to Vitashine Vitamin D3 (vegan-source)
  • revise source of calcium from calcium lactate gluconate to calcium citrate
  • revise source of magnesium from magnesium gluconate to magnesium citrate
  • revise source of manganese from manganese aspartate to manganese gluconate
  • revise source of chromium from chromium picolinate to chromium polynicotinate
  • revise source of molybdenum from molybdenum aspartate to molybdenum citrate
  • new fruit and vegetable blend including: strawberry fruit, tart cherry fruit, blackberry fruit, blueberry fruit, raspberry fruit, beet root, carrot root, spinach leaf, broccoli stem and floret, tomato fruit, kale leaf, cabbage leaf, parsley leaf, brussel sprout edible head, green bell pepper fruit, cucumber whole fruit, celery stalk, garlic bulb, ginger root, green onion, cauliflower curd, asparagus stalk
New Item# LQN22C-C

New NPN: 80081924

New UPC: 7 66298 01934 5

New label V1 		6/1/2018 11/25/2020
Pure Encapsulations Men's Nutrients MEN1C-C
MENN1C-C
 Reformulation: Remove cordyceps sinensis and replace with Astragalus (Astragalus membranaceus) extract (root) 16.6 mg / capsule, remove purple corn (excipient)

New Item# MENN1C-C

New NPN: 80076657

New UPC: 7 66298 01822 5 		12/1/2017 11/25/2020
Pure Encapsulations P5P 50 P51C-C No change Reformulation: increase vitamin B6 (from pyridoxal-5-phosphate)
  • increase label claim from 34 mg / capsule to 50 mg / capsule
New NPN: 80072341

Label updated from V1 to V2 		12/1/2017 11/25/2020
Pure Encapsulations B Complex liquid BCL1C-C No change Reformulation & Packaging Change: addition of lemonade flavour, revision to dose size, remove 1mL dropper
  • increase serving size from 4mL (4 full droppers) to 5mL (1 teaspoon)
  • reduce # servings per bottle from 29 to 28
Revise net qty from 116 mL to 140 mL

Increase bottle size from 120mL to 150mL Amber Glass

New NPN: 80077678

Label updated from V4 to V5 		11/1/2017 11/25/2020
Pure Encapsulations Thyroid Support Complex TS6C-C
TS26C-C
 Reformulation: change source of iodine
  • revise source of iodine from kelp to potassium iodide
New Item# TS26C-C

New NPN: 80026097

New UPC: 7 66298 01862 1

New label V1 		11/1/2017 11/25/2020
Pure Encapsulations PureLean Fibre PLF3C-C
PLFX3C-C
 Reformulation: Defatted rice bran removed and replaced with the prebiotic PreticX XOS
  • added PreticX™ xylooligosaccharides (350 mg)
Revised net weight: 345.6 g

Updated risk information (per product license requirements)

New Item# ANR31C-C

New NPN: 80074260

New UPC: 7 66298 11797 3

New label V1 		7/1/2017 11/25/2020
Pure Encapsulations Century Gothic EX1C-C
EX21C-C
 Reformulation: Remove cordyceps sinensis and replace with Panax ginseng root extract 200 mg per capsule; remove purple corn from other ingredients

New Item# EX21C-C

New NPN: 80071536

New UPC: 7 66298 01803 4

New label V1 		7/1/2017 11/25/2020
Pure Encapsulations Amino-NR ANR21C-C Reformulation: add L-tryptophan (11 mg)

New Item# ANR31C-C

New NPN: 80070020

New UPC: 7 66298 11799 6 		6/1/2017 11/25/2020
Pure Encapsulations HM Complex HM9C-C
HMC9C-C
 Reformulation: Removing 66 mg cilantro per cap and replacing with 66 mg broccoli sprout concentrate (standardized to contain 264 mcg sulforaphane); changing serving size from 2 caps 2 times daily to 3 capsules

New Item# HMC9C-C

New NPN: 80073700

New UPC: 7 66298 01811 9

New Label V1 		6/1/2017 11/25/2020
Pure Encapsulations PhytoBalance II MP6C-C
PHB6C-C
 Reformulation & Brand Name Change: Dong quai removed and replaced with 140 mg Sage (Salvia officianalis) extract (leaf) standardized to contain 4% rosmarinic acid); licorice decreased to 80 mg; motherwort decreased to 80 mg, chaste tree decreased to 40 mg; Added grape (Vitis vinifera) extract (seed) standardized to contain 92% polyphenols 120 mg

New brand name: PhytoBalance II
  • increased capsule size from size "0" to size "00"
  • revise excipients, add cellulose, maltodextrin & tricalcium phosphate
New Item# PHB6C-C

New NPN: 80079473

New UPC: 7 66298 01904 8 		11/25/2020